Desmoglein 1 Antibody

ProSci
Product Code: PSI-42-180
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-42-180-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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42-180 (3.8ug/ml) staining of paraffin embedded Human Skin. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

42-180 (3.8ug/ml) staining of paraffin embedded Human Skin. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Further Information

Additional Names:
DSG1, desmoglein 1, CDHF4, DG1, DSG, desmosomal glycoprotein 1, pemphigus foliaceus antigen
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments in lysates of cell lines A431, HeLa, K562 and MOLT4 gave no specific signal but low background (at antibody concentration up to 1ug/ml).Immunohistochemistry:In paraffin embedded Human Skin showsstaining of the cellular membranes of keratinocytes. Recommended concentration, 4-6ug/ml.
Background References:
  • Nilles L.A., Parry D.A., Powers E.E., Angst B.D., Wagner R.M., Green K.J Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome J. Cell Sci. 1991 Aug 99 ( Pt 4): 809-21
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-YTTSDTLKPSVHVHD
NCBI Gene ID #:
1828
NCBI Official Name:
desmoglein 1
NCBI Official Symbol:
DSG1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001933.2
Protein GI Number:
119703744
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction
Swissprot #:
Q02413