GGCX Antibody
| Code | Size | Price |
|---|
| PSI-42-100-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
GGCX, gamma-glutamyl carboxylase, FLJ26629, VKCFD1, vitamin K-dependent gamma-carboxylase
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Approx 85kDa band observed in Human Muscle lysates (calculated MW of 85kDa according to NP_000812.2). Recommended concentration: 0.3-1ug/ml.Immunohistochemistry:In paraffin embedded Human Kidney shows distinct staining in the cytoplasm of epthelial cells. Recommended concentration, 5-10ug/ml.
Background References:
- Li Q, Grange DK, Armstrong NL, Whelan AJ, Hurley MY, Rishavy MA, Hallgren KW, Berkner KL, Schurgers LJ, Jiang Q, Uitto J, Mutations in the GGCX and ABCC6 genes in a family with pseudoxanthoma elasticum-like phenotypes. J Invest Dermatol. 2009 Mar;129(3):553-63. Epub 2008 Sep 18.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Dog
Immunogen:
The immunogen for this antibody is: C-PPESNPDPVHSE
NCBI Gene ID #:
2677
NCBI Official Name:
gamma-glutamyl carboxylase
NCBI Official Symbol:
GGCX
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000812.2, NP_001135741.1
Protein GI Number:
21361163
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
SPECIFICITY:
This antibody is expected to recognize both isoforms (NP_000812.2; NP_001135741.1).
Swissprot #:
P38435