HTR1A Antibody

ProSci
Product Code: PSI-42-342
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-42-342-0.1mg0.1mg£505.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Further Information

Additional Names:
HTR1A, 5-hydroxytryptamine (serotonin) receptor 1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, 5-HT-1A, 5-HT1a receptor, 5-hydroxytryptamine receptor 1A, G protein coupled receptor, G-21, OTTHUMP00000221821, guanine nucleotide-binding regulatory protein-coupled receptor, serotonin receptor 1A
Application Note:
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Preliminary experiments gave bands at approx 37kDa and 35kDa in Human Brain (Hippocampus, Substantia nigra) lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 46.1kDa according to NP_000515.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human
Immunogen:
The immunogen for this antibody is: C-QPKKSVNGESGSRN
NCBI Gene ID #:
3350
NCBI Official Name:
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
NCBI Official Symbol:
HTR1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000515.2
Protein GI Number:
55956923
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction ,Neuroscience ,Cancer
Swissprot #:
P08908