KCNMA1 Antibody

ProSci
Product Code: PSI-42-044
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-42-044-0.1mg0.1mg£505.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Further Information

Additional Names:
KCNMA1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, BKTM, DKFZp686K1437, KCa1.1, MGC71881, MaxiK, SAKCA, SLO, SLO-ALPHA, SLO1, mSLO1, BKCA alpha subunit, Drosophila slowpoke-like, OTTHUMP00000060198, OTTHUMP00000064154, OTTHUMP00000064155, OTTHUMP00000064156, OTTHUMP00000064157, OTTHUMP00000064158, OTTHUMP00000064159, OTTHUMP00000064160, OTTHUMP00000064161, OTTHUMP00000064162, OTTHUMP00000064164, OTTHUMP00000064165, bA205K10.1 (potassium large conductance calcium-activaed channel, subfamily M, alpha member 1), large conductance calcium-activated potassium channel subfamily M alpha member 1, stretch-activated Kca channel
Application Note:
Peptide ELISA: antibody detection limit dilution 1:2000.Western Blot:Preliminary experiments in Human Brain (Cerebellum, Cerebral Cortex, Frontal Cortex) lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Background References:
  • Yuan C, O\1Connell RJ, Wilson A, Pietrzykowski AZ, Treistman SN. Acute alcohol tolerance is intrinsic to the BKCa protein, but is modulated by the lipid environment. J Biol Chem. 2008 Feb 22;283(8):5090-8. Epub 2007 Dec 15.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Mouse, Rat, Cow
Immunogen:
The immunogen for this antibody is: C-RESRDKQNRKEMVYR
NCBI Gene ID #:
3778
NCBI Official Name:
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
NCBI Official Symbol:
KCNMA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001014797.1
Protein GI Number:
62388890
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction ,Immunology ,Innate Immunity
SPECIFICITY:
This antibody is expected to recognize isoform a (NP_001014797.1) only.
Swissprot #:
Q12791