IL-10 Monoclonal Antibody
| Code | Size | Price |
|---|
| PSI-32-227-0.1mg | 0.1mg | £452.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1.kappa
Antibody Clonality: Monoclonal
Antibody Clone: 3C12C12
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
to IL-10 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cytokine synthesis inhibitory factor, IL-10, CSIF, TGIF, GVHDS, IL10A
Application Note:
Western Blot:1:500 - 1,000
ELISA:Determining optimal working dilutions by titration test.
ELISA:Determining optimal working dilutions by titration test.
Background:
Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down- regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Background References:
- Vieira P, et al. PNAS, 1991.88:1172-1176.
Buffer:
Purified antibody in PBS containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified recombinant human IL-10 expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
3586
NCBI Official Name:
interleukin 10
NCBI Official Symbol:
IL10
NCBI Organism:
Homo sapiens
Protein Accession #:
P22301
Protein GI Number:
124292
Purification:
Antibody is purified by protein A affinity chromatography.
Research Area:
Immunology ,Innate Immunity
Swissprot #:
P22301
User NOte:
Optimal dilutions for each application to be determined by the researcher.