HCK Monoclonal Antibody

ProSci
Product Code: PSI-32-168
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-32-168-0.1mL0.1mL£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 3D12E10
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
HCK monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis using HCK monoclonal antibody against truncated HCK - His recombinant protein and full - length HCK / GFP transfected CHO - K1 cell lysate.
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Western blot analysis using HCK monoclonal antibody against truncated HCK - His recombinant protein and full - length HCK / GFP transfected CHO - K1 cell lysate.

Further Information

Additional Names:
Hematopoietic cell kinaseJTK9, p59Hck, p61Hck
Application Note:
Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Background:
Hemopoietic cell kinase.The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.
Background References:
  • J Clin Gastroenterol. 2007 Aug;41(7):667-70.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified truncated recombinant HCK-His fusion protein is expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
3055
NCBI Official Name:
hemopoietic cell kinase
NCBI Official Symbol:
HCK
NCBI Organism:
Homo sapiens
Protein Accession #:
P08631
Protein GI Number:
20141296
Research Area:
Immunology ,Signal Transduction
Swissprot #:
P08631
User NOte:
Optimal dilutions for each application to be determined by the researcher.