S100A Monoclonal Antibody
| Code | Size | Price |
|---|
| PSI-32-213-0.1mL | 0.1mL | £560.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 2C8B8
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
S100A monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
S100A, S-100 protein alpha chainS100, S100A, S100-alpha
Application Note:
Dilution
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test.
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test.
Background:
S100 calcium binding protein A1 (S100-alpha/ S100A1), The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Background References:
- Koenig A, Wojcieszyn J, Weeks BR, et al. Vet Pathol. 2001;38(4):427-35.
- Hoyaux D, Decaestecker C, Heizmann CW, et al. Brain Res. 2000;867(1-2):280-8.
- Pingerelli PL, Mizukami H, Wagner AS, et al. J Protein Chem. 1990;9(2):169-75.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified truncated recombinant S100A expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
6271
NCBI Official Name:
S100 calcium binding protein A1
NCBI Official Symbol:
S100A1
NCBI Organism:
Homo sapiens
Protein Accession #:
P23297
Protein GI Number:
134136
Purification:
Antibody is purified by protein A affinity chromatography.
Swissprot #:
P23297
User NOte:
Optimal dilutions for each application to be determined by the researcher.