PAX8 Antibody

ProSci
Product Code: PSI-46-142
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-142-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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HEK293 overexpressing PAX8A and probed with 46-142 (mock transfection in first lane).

HEK293 overexpressing PAX8A and probed with 46-142 (mock transfection in first lane).

Further Information

Additional Names:
PAX8, paired box gene 8, HGNC:8622 , paired domain gene 8, paired box 8
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:In transfected HEK293 transiently expressing PAX8A a band of approx. 55kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.5-1.5ug/ml.
Background References:
  • Castro P, Rebocho AP, Soares RJ, Magalhaes J, Roque L, Trovisco V, Vieira de Castro I, Cardoso-de-Oliveira M, Fonseca E, Soares P, Sobrinho-Simoes M. PAX8-PPAR{gamma} rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma. J Clin Endocrinol Metab. 2005 Oct 11;
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-AQPGSDKRKMDD
NCBI Gene ID #:
7849
NCBI Official Name:
paired box 8
NCBI Official Symbol:
PAX8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_003457.1, NP_039245.1, NP_039246.1, NP_039247.1, NP_054698.1
Protein GI Number:
5803117
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognise all reported isoforms (NP_003457.1; NP_039245.1; NP_039246.1; NP_039247.1; NP_054698.1)
Swissprot #:
Q06710