PDE11A Antibody

ProSci
Product Code: PSI-46-150
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-150-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-150 (1ug/ml) staining of Human Prostate lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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46-150 (1ug/ml) staining of Human Prostate lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
PDE11A, phosphodiesterase 11A , FLJ23693, MGC133355, MGC133356, PPNAD2 , cAMP and cGMP cyclic nucleotide phosphodiesterase 11A, cyclic nucleotide phosphodiesterase 11A, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Application Note:
Peptide ELISA: antibody detection limit dilution 1:2000.Western Blot:Approx 60-65kDa band observed in Human Skeletal Muscle and Human Prostate lysates (calculated MW of 65.7kDa according to NP_001070826.1). Recommended concentration: 0.5-1.5ug/ml.Immunohistochemistry:Paraffin embedded Human Prostate. Recommended concentration: 10ug/ml.
Background References:
  • Horvath A, Boikos S, Giatzakis C, Robinson-White A, Groussin L, Griffin KJ, Stein E, Levine E, Delimpasi G, Hsiao HP, Keil M, Heyerdahl S, Matyakhina L, Libe R, Fratticci A, Kirschner LS, Cramer K, Gaillard RC, Bertagna X, Carney JA, Bertherat J, Bossis I, Stratakis CA. A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia. Nat Genet. 2006 Jul;38(7):794-800. Epub 2006 Jun 11.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog
Immunogen:
The immunogen for this antibody is: C-NSFKESMEKSSYSD
NCBI Gene ID #:
50940
NCBI Official Name:
phosphodiesterase 11A
NCBI Official Symbol:
PDE11A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_058649.3 , NP_001070665.1, NP_001070826.1, NP_001070664.1
Protein GI Number:
116536085
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognise all four reported isoforms (NP_058649.3 ; NP_001070665.1; NP_001070826.1; NP_001070664.1).
Swissprot #:
Q9HCR9