SETDB2 Antibody

ProSci
Product Code: PSI-46-361
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-361-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-361 (1.5ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

46-361 (1.5ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
SETDB2, CLLD8, SET domain, bifurcated 2, CLLL8 protein, C13orf4, CLLL8, DKFZp586I0123, DKFZp761J1217, KMT1F, chronic lymphocytic leukemia deletion region 8, lysine N-methyltransferase 1F, histone-lysine N-methyltransferase SETDB2
Application Note:
Peptide ELISA: antibody detection limit dilution 1:8000.Western Blot:Approx 80kDa band observed in Human Heart lysates (calculated MW of 81.9kDa according to NP_114121.1). Recommended concentration: 1.5-4.5ug/ml. This product is not suitable in WB on Mouse Heart and Rat Heart lysates.
Background References:
  • Mabuchi H, Fujii H, Calin G, Alder H, Negrini M, Rassenti L, Kipps TJ, Bullrich F, Croce CM. Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia. Cancer Res. 2001 Apr 1;61(7):2870-7.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: GEKNGDAKTFWME-C
NCBI Gene ID #:
83852
NCBI Official Name:
SET domain, bifurcated 2
NCBI Official Symbol:
SETDB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_114121.2, NP_001153780.1
Protein GI Number:
13994282
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognize both reported isoforms (NP_114121.2; NP_001153780.1).
Swissprot #:
Q96T68