TARDBP Antibody

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ProSci
Product Code: PSI-46-778
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-778-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-778 (0.3ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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46-778 (0.3ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Documents

Further Information

Additional Names:
TARDBP, TAR DNA binding protein, ALS10, TDP-43, OTTHUMP00000002171, TAR DNA-binding protein-43
Application Note:
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Approx. 45kDa band observed in lysates of cell lines Jurkat (calculated MW of 44.7kDa according to NP_031401.1). A slightly larger protein is detected in some regions of the Brain. Recommended concentration: 0.3-1ug/ml.
Background References:
  • Zhang YJ, Xu YF, Dickey CA, Buratti E, Baralle F, Bailey R, Pickering-Brown S, Dickson D, Petrucelli L. Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. J. Neurosci. 2007 Sep 27 (39): 10530-4.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: C-HISNAEPKHNSNRQ
NCBI Gene ID #:
23435
NCBI Official Name:
TAR DNA binding protein
NCBI Official Symbol:
TARDBP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_031401.1
Protein GI Number:
6678271
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience ,HIV and HIV Related ,Virus Related ,HIV and HIV Related
SPECIFICITY:
.
Swissprot #:
Q13148