T-cell Differentiation Protein Antibody

ProSci
Product Code: PSI-46-473
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-473-0.1mg0.1mg£505.00
Quantity:
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Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Further Information

Additional Names:
MAL, mal, T-cell differentiation protein , T-cell differentiation protein MAL, T-lymphocyte maturation-associated protein, myelin and lymphocyte protein
Application Note:
Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Preliminary experiments gave an approx 35kDa band in Human Thymus and Thyroid Gland lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 16.7kDa according to NP_002362.1. The 35kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
  • Khor CC, et al A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. Nat Genet. 2007 Apr;39(4):523-528. Epub 2007 Feb 25. PMID: 17322885 [PubMed - as supplied by publisher]
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Mouse, Rat
Immunogen:
The immunogen for this antibody is: C-QDGFTYRHYHEN
NCBI Gene ID #:
4118
NCBI Official Name:
mal, T-cell differentiation protein
NCBI Official Symbol:
MAL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_002362.1, NP_071884.1
Protein GI Number:
4505091
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognise isoform a (NP_002362.1) and isoform c (NP_071884.1).
Swissprot #:
P21145