XBP1 Antibody

ProSci
Product Code: PSI-46-606
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-606-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-606 (1ug/ml) staining of nuclear HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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46-606 (1ug/ml) staining of nuclear HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
XBP1, TREB5, X-box binding protein 1 , XBP2, OTTHUMP00000028682, X-box-binding protein-1
Application Note:
Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Approx 38kDa band observed in Nuclear lysates of cell line HeLa (calculated MW of 40.1kDa according to NP_001073007.1). Recommended concentration: 1-3ug/ml.Immunohistochemistry:Paraffin embedded Human Breast. Recommended concentration: 5ug/ml.
Background References:
  • Yokouchi M, Hiramatsu N, Hayakawa K, Okamura M, Du S, Kasai A, Takano Y, Shitamura A, Shimada T, Yao J, Kitamura M. Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response. J Biol Chem. 2007 Dec 17;
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog
Immunogen:
The immunogen for this antibody is: C-NHSWEDTFANELFPQ
NCBI Gene ID #:
7494
NCBI Official Name:
X-box binding protein 1
NCBI Official Symbol:
XBP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001073007.1
Protein GI Number:
118640873
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognise isoform XBP1(S) (NP_001073007.1) only.
Swissprot #:
P17861