JUN Antibody
| Code | Size | Price |
|---|
| PSI-XW-7318-0.05mg | 0.05mg | £801.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
JUN antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transcription factor AP-1, Activator protein 1, AP1, AP-1, c-Jun, Jun
Application Note:
Jun antibody can be used for the detection of Jun by Western blot, may also work for IHC and ICC.
Background:
V-jun avian sarcoma virus 17 oncogene homolog; Jun activation domain binding protein. The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. The JUN gene product has also been shown to be structurally and functionally identical to the enhancer binding protein, AP-1; thus AP-1 may be encoded by JUN. The JUN protein interacts directly with specific target DNA sequences to regulate gene expression. JUN has been mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Background References:
- Eferl, R., Ricci, R., Kenner, L., Zenz, R., David, J. -P., Rath, M., Wagner, E. F. Liver tumor development: c-Jun antagonizes the proapoptotic activity of p53. Cell 112: 181-192, 2003.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
1-240
NCBI Gene ID #:
3725
NCBI Official Name:
jun proto-oncogene
NCBI Official Symbol:
JUN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35.7 kDa (calculated)
Protein Accession #:
NP_002219.1
Protein GI Number:
4758616, 386839
Purification:
Antigen affinity-purified
Research Area:
Signal Transduction
Swissprot #:
P05412
User NOte:
Optimal dilutions for each application to be determined by the researcher.