TLR2 Antibody
| Code | Size | Price |
|---|
| PSI-XW-7622-0.05mg | 0.05mg | £765.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
TLR2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
TIL4, Toll-like receptor 2, TIL4, CD282,
Application Note:
TLR2 antibody can be used for the detection of TLR2 by Western blot, may also work for IHC and ICC.
Background:
Toll-like receptor 2; toll/interleukin 1 receptor-like 4 [Homo sapiens]. This protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-κB.
Background References:
- Aliprantis, A. O., Yang, R. -B., Mark, M. R., Suggett, S., Devaux, B., Radolf, J. D., Klimpel, G. R., Godowski, P., Zychlinsky, A. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 285: 736-739, 1999.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
215-410
NCBI Gene ID #:
7097
NCBI Official Name:
toll-like receptor 2
NCBI Official Symbol:
TLR2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
89.8 kDa (calculated)
Protein Accession #:
NP_003255.2
Protein GI Number:
19718734
Purification:
Antigen affinity-purified
Research Area:
Innate Immunity
Swissprot #:
O60603
User NOte:
Optimal dilutions for each application to be determined by the researcher.