IL17A Antibody
| Code | Size | Price |
|---|
| PSI-XW-7289-0.05mg | 0.05mg | £801.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
IL17A antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
IGIF, IL1F4, Interleukin-18, Iboctadekin, IL-18, IGIF, IL-1g,
Application Note:
IL17 antibody can be used for the detection of IL-17 by ELISA, Western blot, may also work for IHC and ICC.
Background:
Interleukin 17; cytotoxic T-lymphocyte-associated serine esterase 8. This protein is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-κB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis
Background References:
- Nakae, S., Saijo, S., Horai, R., Sudo, K., Mori, S., Iwakura, Y. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc. Nat. Acad. Sci. 100: 5986-5990, 2003.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
37-193
NCBI Gene ID #:
3606
NCBI Official Name:
interleukin 18 (interferon-gamma-inducing factor)
NCBI Official Symbol:
IL18
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17.5 kDa (calculated)
Protein Accession #:
NP_001553.1
Protein GI Number:
4504653
Purification:
Antigen affinity-purified
Research Area:
Chemokines & Cytokines
Swissprot #:
Q14116
User NOte:
Optimal dilutions for each application to be determined by the researcher.