CBFA2T3 Antibody
| Code | Size | Price |
|---|
| PSI-27-985-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CBFA2T3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
CBFA2T3, ETO2, MTG16, MTGR2, ZMYND4
Application Note:
CBFA2T3 antibody can be used for detection of CBFA2T3 by ELISA at 1:312500. CBFA2T3 antibody can be used for detection of CBFA2T3 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The t (16;21) (q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Background References:
- Powell, J.A., et al., (2002) Genomics 80 (3), 303-310.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CBFA2T3.
NCBI Gene ID #:
863
NCBI Official Name:
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
NCBI Official Symbol:
CBFA2T3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa, 71 kDa
Protein Accession #:
NP_787127
Protein GI Number:
28872805
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
O75082
User NOte:
Optimal dilutions for each application to be determined by the researcher.