TNFRSF18 Antibody
| Code | Size | Price |
|---|
| PSI-31-022-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TNFRSF18 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
TNFRSF18, AITR, GITR, GITR-D, CD357
Application Note:
TNFRSF18 antibody can be used for detection of TNFRSF18 by ELISA at 1:312500. TNFRSF18 antibody can be used for detection of TNFRSF18 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Background References:
- Liu, B., (2008) J. Biol. Chem. 283 (13), 8202-8210.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFRSF18.
NCBI Gene ID #:
8784
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 18
NCBI Official Symbol:
TNFRSF18
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
NP_683700
Protein GI Number:
23238197
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane ,Cancer ,Signal Transduction ,Apoptosis
Swissprot #:
B1AME3
User NOte:
Optimal dilutions for each application to be determined by the researcher.