LMP7 Antibody
| Code | Size | Price |
|---|
| PSI-42-016-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
PSMB8, proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7), D6S216, D6S216E, LMP7, MGC1491, PSMB5i, RING10, beta5i, OTTHUMP00000029420, OTTHUMP00000029421, OTTHUMP00000062981, low molecular weight protein 7, macropain subunit C13, multicatalytic endopeptidase complex subunit C13, protease component C13, proteasome (prosome, macropain) subunit beta type 8 (large multifunctional protease 7), proteasome beta 8 subunit, proteasome catalytic subunit 3i, proteasome subunit Y2, proteasome subunit beta 5i, proteasome-related gene 7
Application Note:
Peptide ELISA: antibody detection limit dilution 1:8000.Western Blot:Approx 22kDa band observed in Human Liver, Lung and Lymph Node lysates (calculated MW of 29.8kDa according to precursor NP_004150.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Schwarz et al, J Immunol. 2000 Jul 15;165(2):768-78. PMID: 10878350. Recommended concentration: 0.01-0.03ug/ml. Primary incubation was 1 hour.Immunohistochemistry:Paraffin embedded Human Spleen. Recommended concentration: 3.75ug/ml.
Background References:
- Deshpande A, Wheeler CM, Hunt WC, Peyton CL, White PS, Valdez YE, Nolan JP. Variation in HLA class I antigen-processing genes and susceptibility to human papillomavirus type 16-associated cervical cancer. The Journal of Infectious Diseases 2008 Feb 197 (3): 371-81.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: C-DVSDLLHQYREANQ
NCBI Gene ID #:
5696
NCBI Official Name:
proteasome (prosome, macropain) subunit, beta type, 8
NCBI Official Symbol:
PSMB8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_004150.1, NP_683720.2
Protein GI Number:
4758970
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
SPECIFICITY:
This antibody is expected to recognize both reported isoforms (NP_004150.1; NP_683720.2).
Swissprot #:
P28062