PAR-1 Antibody

ProSci
Product Code: PSI-46-687
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-687-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-687 (0.3ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

46-687 (0.3ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
MARK2, PAR-1, MAP/microtubule affinity-regulating kinase 2, EMK1, MGC99619, ELKL motif kinase, ELKL motif kinase 1, protein-serine/threonine kinase, serine/threonine kinase
Application Note:
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Approx 70kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 77.6kDa according to NP_004945.3). Recommended concentration: 0.3-1ug/ml.
Background References:
  • Depasquale I, Thompson WD. Prognosis in human melanoma: PAR-1 expression is superior to other coagulation components and VEGF. Histopathology. 2008 Mar;52(4):500-9.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Cow
Immunogen:
The immunogen for this antibody is: C-QNGKDSTAPQR
NCBI Gene ID #:
2011
NCBI Official Name:
MAP/microtubule affinity-regulating kinase 2
NCBI Official Symbol:
MARK2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_004945.4, NP_001156768.1, NP_001156769.1
Protein GI Number:
86990432
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
SPECIFICITY:
This antibody is expected to recognise isoform c (NP_004945.4), isoform e (NP_001156768.1) and isoform f (NP_001156769.1).
Swissprot #:
Q7KZI7