Pmel-17 Antibody

ProSci
Product Code: PSI-46-204
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-204-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-204 (1ug/ml) staining of Human Skin lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.

46-204 (1ug/ml) staining of Human Skin lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.

Further Information

Additional Names:
silver homolog (mouse) , PMEL17, SILV , D12S53E, ME20, SI, SIL, gp100 , Melanocyte protein mel 17, Pmel 17, Silver, mouse, homolog of, silver (mouse homolog) like, silver (mouse homolog)-like, silver homolog
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 26kDa band observed in Human Skin lysates, corresponding to the M-beta fragment of the precursor protein (Leonhardt et al, Mol Biol Cell. 2013 Apr;24(7):964-81.PMID: 23389629). Calculated MW of 70.3kDa according to NP_008859.1. Primary incubation was 1 hour.
Background References:
  • Fowler DM, Koulov AV, Alory-Jost C, Marks MS, Balch WE, Kelly JW. Functional amyloid formation within mammalian tissue. PLoS Biol. 2006 Jan;4(1):e6.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: CPIGENSPLLSGQQ
NCBI Gene ID #:
6490
NCBI Official Name:
premelanosome protein
NCBI Official Symbol:
PMEL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_008859.1
Protein GI Number:
5902084
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
.
Swissprot #:
P40967