TRIM3 Antibody

ProSci
Product Code: PSI-28-166
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-28-166-100ul100ul£609.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TRIM3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human kidney.
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Antibody used in IHC on Human kidney.

Further Information

Additional Names:
TRIM3, BERP, HAC1, RNF22, RNF97
Application Note:
TRIM3 antibody can be used for detection of TRIM3 by ELISA at 1:1562500. TRIM3 antibody can be used for detection of TRIM3 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The protein encoded by TRIM3 is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport.
Background References:
  • Reymond, A., et al., (2001) EMBO J. 20 (9), 2140-2151.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIM3.
NCBI Gene ID #:
10612
NCBI Official Name:
tripartite motif containing 3
NCBI Official Symbol:
TRIM3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
81 kDa
Protein Accession #:
NP_006449
Protein GI Number:
32454739
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Cancer ,Neuroscience
Swissprot #:
Q6ZTE7
User NOte:
Optimal dilutions for each application to be determined by the researcher.