KSHV K8a Monoclonal Antibody

ProSci
Product Code: PSI-32-182
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-32-182-0.1mL0.1mL£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: 8C12G10G1
Regulatory Status: RUO
Target Species: Virus
Applications:
  • Immunocytochemistry (ICC)
  • Western Blot (WB)
Storage:
KSHV K8? monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis using KSHV K8alpha monoclonal antibody against TPA induced BCBL - 1 cell lysate.
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Western blot analysis using KSHV K8alpha monoclonal antibody against TPA induced BCBL - 1 cell lysate.

Further Information

Additional Names:
E3 SUMO-protein ligase K-bZIP
Application Note:
Western Blot:Dilution 1:500 - 1,000
ICC:Dilution 1:50 - 1:100
Determining optimal working dilutions by titration test.
Background:
Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi?s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman?s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV K8 and K8.1 open reading frames are juxtaposed and span from nucleotide (nt) 74850 to 76695 of the virus genome. A K8 pre-mRNA overlaps the entire K8.1 coding region, and alternative splicing of KSHV K8 and K8.1 pre-mRNAs each produces three isoforms (α,β, and γ) of the mRNAs.
Background References:
  • James J et al. Proc. Natl. Acad. Sci Vol. 1996. 93, pp. 14862-14867.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified recombinant human KSHV K8α expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
4961462
NCBI Official Name:
bZIP transcription factor
NCBI Official Symbol:
K8
NCBI Organism:
Human herpesvirus 8
Protein Accession #:
Q2HR82
Protein GI Number:
123831254
Research Area:
Infectious Disease
Swissprot #:
Q2HR82
User NOte:
Optimal dilutions for each application to be determined by the researcher.