PHOX2B Antibody

ProSci
Product Code: PSI-46-976
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-976-0.1mg0.1mg£505.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Further Information

Additional Names:
PHOX2B, paired-like homeobox 2b, NBPhox, PMX2B, PHOX2B homeodomain protein, neuroblastoma paired-type homeobox protein, paired mesoderm homeobox 2b
Application Note:
Peptide ELISA: antibody detection limit dilution 1:1000.Western Blot:Preliminary experiments in Human Brain (Cerebellum) lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Background References:
  • McGaughey DM, Vinton RM, Huynh J, Al-Saif A, Beer MA, McCallion AS. Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b. Genome Res. 2008 Feb;18(2):252-60. Epub 2007 Dec 10.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Mouse
Immunogen:
The immunogen for this antibody is: C-SRDDESKEAKSTDP
NCBI Gene ID #:
8929
NCBI Official Name:
paired-like homeobox 2b
NCBI Official Symbol:
PHOX2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_003915.2
Protein GI Number:
12707580
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction
Swissprot #:
Q99453