SART3 Antibody
| Code | Size | Price |
|---|
| PSI-29-012-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SART3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
SART3, P100, p110, DSAP1, TIP110, p110(nrb), RP11-13G14
Application Note:
SART3 antibody can be used for detection of SART3 by ELISA at 1:62500. SART3 antibody can be used for detection of SART3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing.
Background References:
- Liu, Y., (2002) J. Biol. Chem. 277 (26), 23854-23863.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SART3.
NCBI Gene ID #:
9733
NCBI Official Name:
squamous cell carcinoma antigen recognized by T cells 3
NCBI Official Symbol:
SART3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa, 110 kDa
Protein Accession #:
AAK69347
Protein GI Number:
14579643
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,RNA Binding ,Cancer
Swissprot #:
Q15020-2
User NOte:
Optimal dilutions for each application to be determined by the researcher.