TNKS Antibody

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ProSci
Product Code: PSI-42-019
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-42-019-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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HEK293 overexpressing TANK1 (lane 2) and TANK2 (lane 4) and probed with 42-019 (mock transfection in first lane). Lane three is empty. Lower panel shows the same lysates probed for alpha-Actin to show protein levels. Primary incubation (0.5ug/ml) was ove
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HEK293 overexpressing TANK1 (lane 2) and TANK2 (lane 4) and probed with 42-019 (mock transfection in first lane). Lane three is empty. Lower panel shows the same lysates probed for alpha-Actin to show protein levels. Primary incubation (0.5ug/ml) was ove

Documents

Further Information

Additional Names:
TNKS, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, HGNC:11941, PARP-5a, PARP5A, PARPL, TIN1, TINF1, TNKS1
Application Note:
Western Blot:In transfected HEK293 transiently expressing TANK1 a band of approx. 142kDa is observed. This band is not observed in the non-transfected HEK293. The calculated molecular size is 142 kDa according to NP_003738.2. Recommended concentration, 0.5-1.5ug/ml.
Background References:
  • Seimiya H, Muramatsu Y, Ohishi T, Tsuruo T. Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics. Cancer Cell. 2005 Jan;7(1):25-37.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: RECOMBINANT
NCBI Gene ID #:
8658
NCBI Official Name:
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
NCBI Official Symbol:
TNKS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_003738.2
Protein GI Number:
87239981
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by affinity chromatography using Protein G.
Research Area:
Homeostasis
SPECIFICITY:
Fusion protein containing 120aa amino acids from N Terminal region (according to NP_003738.2)
Swissprot #:
O95271