PRKAG3 Antibody

ProSci
Product Code: PSI-46-941
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-941-0.1mg0.1mg£505.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Further Information

Additional Names:
PRKAG3 , protein kinase, AMP-activated, gamma 3 non-catalytic subunit , AMPKG3, 5'-AMP-activated protein kinase, gamma-3 subunit, AMP-activated protein kinase, non-catalytic gamma-3 subunit, AMPK gamma-3 chain
Application Note:
Peptide ELISA: antibody detection limit dilution 1:8000.Western Blot:Preliminary experiments in Human Heart, Skeletal Muscle and Pancreas lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Background References:
  • Costford SR, Kavaslar N, Ahituv N, Chaudhry SN, Schackwitz WS, Dent R, Pennacchio LA, McPherson R, Harper ME. Gain-of-function R225W mutation in human AMPKgamma3 causing increased glycogen and decreased triglyceride in skeletal muscle. PLoS ONE. 2007 Sep 19;2(9):e903.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Cow
Immunogen:
The immunogen for this antibody is: C-KLGWDDELRKPGAQ
NCBI Gene ID #:
53632
NCBI Official Name:
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
NCBI Official Symbol:
PRKAG3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_059127.2
Protein GI Number:
47132577
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction ,Homeostasis
Swissprot #:
Q9UGI9