TCF7L1 Antibody
| Code | Size | Price |
|---|
| PSI-27-114-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TCF7L1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
TCF7L1, TCF-3, TCF3
Application Note:
TCF7L1 antibody can be used for detection of TCF7L1 by ELISA at 1:1562500. TCF7L1 antibody can be used for detection of TCF7L1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
Background References:
- Hillier, L.W., (2005) Nature 434 (7034), 724-731.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCF7L1.
NCBI Gene ID #:
83439
NCBI Official Name:
transcription factor 7-like 1 (T-cell specific, HMG-box)
NCBI Official Symbol:
TCF7L1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
NP_112573
Protein GI Number:
13786123
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Signal Transduction
Swissprot #:
Q9HCS4
User NOte:
Optimal dilutions for each application to be determined by the researcher.