AUTS2 Antibody

ProSci
Product Code: PSI-46-970
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-970-0.1mg0.1mg£565.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Further Information

Additional Names:
AUTS2, autism susceptibility candidate 2, KIAA0442, MGC13140, autism-related protein 1
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments gave an approx 60kDa band in Human Brain (Cerebral Cortex and Frontal Cortex) lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 139kDa according to NP_056385.1 and of 136kDa according to NP_001120703.1. The 60kDa band was successfully blocked by incubation with the immunizing peptide.
Background References:
  • Bakkaloglu B, O'Roak BJ, Louvi A, Gupta AR, Abelson JF, Morgan TM, Chawarska K, Klin A, Ercan-Sencicek AG, Stillman AA, Tanriover G, Abrahams BS, Duvall JA, Robbins EM, Geschwind DH, Biederer T, Gunel M, Lifton RP, State MW. Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders. Am J Hum Genet. 2008 Jan;82(1):165-73.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Mouse, Dog
Immunogen:
The immunogen for this antibody is: C-ERPPSHTLKDIEAR
NCBI Gene ID #:
26053
NCBI Official Name:
autism susceptibility candidate 2
NCBI Official Symbol:
AUTS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_056385.1, NP_001120703.1
Protein GI Number:
17864090
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
SPECIFICITY:
This antibody is expected to recognize isoforms 1 and 2 (NP_056385.1 and NP_001120703.1 resp.).
Swissprot #:
Q8WXX7