KPNA6 Antibody

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ProSci
Product Code: PSI-46-860
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-860-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-860 (0.1ug/ml) staining of Human Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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46-860 (0.1ug/ml) staining of Human Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Documents

Further Information

Additional Names:
KPNA6 , karyopherin alpha 6 (importin alpha 7) , FLJ11249, IPOA7, KPNA7, MGC17918, importin alpha 7 subunit, importin-alpha-S2, karyopherin alpha 6
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 60kDa band observed in Human Skeletal Muscle lysates (calculated MW of 60.0kDa according to NP_036448.1). Recommended concentration:0.1-0.3ug/ml. Some minor background is detected and is blocked by the immunizing peptide. We call for caution when used for other assays than Western blot.Immunohistochemistry:In paraffin embedded Human Adrenal Gland shows staining of cytoplasm and some nuclear membrane (nuclear pores). Recommended concentration, 3-6ug/ml.
Background References:
  • Ma J, Cao X. Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements. Cell Signal. 2006 Aug;18(8):1117-26. Epub 2005 Nov 18.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: C-STTGESVITREMVE
NCBI Gene ID #:
23633
NCBI Official Name:
karyopherin alpha 6 (importin alpha 7)
NCBI Official Symbol:
KPNA6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_036448.1
Protein GI Number:
6912478
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction
SPECIFICITY:
.
Swissprot #:
O60684