CCDC50 Antibody
| Code | Size | Price |
|---|
| PSI-30-864-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CCDC50 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
CCDC50, C3orf6, DFNA44, YMER
Application Note:
CCDC50 antibody can be used for detection of CCDC50 by ELISA at 1:1562500. CCDC50 antibody can be used for detection of CCDC50 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling.
Background References:
- Bohgaki, M., (2008) Biochim. Biophys. Acta 1783 (5), 826-837.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCDC50.
NCBI Gene ID #:
152137
NCBI Official Name:
coiled-coil domain containing 50
NCBI Official Symbol:
CCDC50
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
NP_848018
Protein GI Number:
41281911
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q8IVM0
User NOte:
Optimal dilutions for each application to be determined by the researcher.