SCN5A Antibody

ProSci
Product Code: PSI-46-343
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-343-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-343 (10ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

46-343 (10ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Further Information

Additional Names:
SCN5A, CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, ICCD, HH1, IVF, LQT3, SSS1, PFHB1, SSS1, sodium channel, voltage-gated, type V, alpha subunit, Nav1.5, sodium channel, voltage-gated, type V, alpha (long QT syndrome 3), cardiac sodium channel alpha subunit, sodium channel, voltage-gated, type V, alpha polypeptide (long (electrocardiographic) QT syndrome 3), VF1, cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit, sodium channel protein type V alpha subunit, voltage-gated sodium channel type V alpha
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments in lysates of Human Breast and Heart tissues gave no specific signal but low background (at antibody concentration up to 1ug/ml).Immunohistochemistry:Paraffin embedded Human Brain (Cortex). Recommended concentration: 10ug/ml.
Background References:
  • Olson TM, Michels VV, Ballew JD, Reyna SP, Karst ML, Herron KJ, Horton SC, Rodeheffer RJ, Anderson JL. Sodium channel mutations and susceptibility to heart failure and atrial fibrillation. JAMA. 2005 Jan 26;293(4):447-54.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Cow
Immunogen:
The immunogen for this antibody is: C-ETDDQSPEKIN
NCBI Gene ID #:
6331
NCBI Official Name:
sodium channel, voltage-gated, type V, alpha subunit
NCBI Official Symbol:
SCN5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_932173.1, NP_000326.2, NP_001092874.1, NP_001092875.1, NP_001153632.1, NP_001153633.1
Protein GI Number:
37622907
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer ,Infectious Disease
SPECIFICITY:
This antibody is expected to recognise all reported isoforms (NP_932173.1; NP_000326.2; NP_001092874.1; NP_001092875.1).
Swissprot #:
Q14524