TNKS2 Antibody

ProSci
Product Code: PSI-42-018
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-42-018-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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HEK293 overexpressing TANK2 (lane 4) and TANK1 (lane 2) and probed with 42-018 (mock transfection in first lane). Lane three is empty. Lower panel shows the same lysates probed for alpha-Actin to show protein levels. Primary incubation (0.5ug/ml) was ove

HEK293 overexpressing TANK2 (lane 4) and TANK1 (lane 2) and probed with 42-018 (mock transfection in first lane). Lane three is empty. Lower panel shows the same lysates probed for alpha-Actin to show protein levels. Primary incubation (0.5ug/ml) was ove

Further Information

Additional Names:
TNKS2, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, PARP-5b, PARP-5c, PARP5B, PARP5C, TANK2, TNKL, tankyrase 2
Application Note:
Western Blot:In transfected HEK293 transiently expressing TANK2 a band of approx. 127kDa is observed. This band is not observed in the non-transfected HEK293. The calculated molecular size is 127 kDa according to NP_079511.1. Recommended concentration, 0.5-1.5ug/ml.
Background References:
  • Sidorova N, Zavalishina L, Kurchashova S, Korsakova N, Nazhimov V, Frank G, Kuimov A. Immunohistochemical detection of tankyrase 2 in human breast tumors and normal renal tissue. Cell Tissue Res. 2006 Jan;323(1):137-45. Epub 2005 Sep 3.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog
Immunogen:
The immunogen for this antibody is: RECOMBINANT2
NCBI Gene ID #:
80351
NCBI Official Name:
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
NCBI Official Symbol:
TNKS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_079511.1
Protein GI Number:
13376842
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by affinity chromatography using Protein G.
Research Area:
Signal Transduction
SPECIFICITY:
Fusion protein containing 73 aas from region aa800-900 (according to NP_079511.1). No crossreactivity expected with TANK1.
Swissprot #:
Q9H2K2