SIL1 Antibody

ProSci
Product Code: PSI-31-363
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-31-363-100ul100ul£662.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SIL1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human Muscle.
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Antibody used in IHC on Human Muscle.

Further Information

Additional Names:
SIL1, BAP, MSS, ULG5
Application Note:
SIL1 antibody can be used for detection of SIL1 by ELISA at 1:62500. SIL1 antibody can be used for detection of SIL1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SIL1 is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in its gene have been associated with Marinesco-Sjogren syndrome.This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.
Background References:
  • Anttonen, A.K., (2005) Nat. Genet. 37 (12), 1309-1311.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIL1.
NCBI Gene ID #:
64374
NCBI Official Name:
SIL1 nucleotide exchange factor
NCBI Official Symbol:
SIL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa, 52 kDa
Protein Accession #:
NP_071909
Protein GI Number:
11968009
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane
Swissprot #:
Q9H173
User NOte:
Optimal dilutions for each application to be determined by the researcher.