PARP3 Antibody

ProSci
Product Code: PSI-27-941
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-27-941-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store PARP3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human Stomach.
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Antibody used in IHC on Human Stomach.

Further Information

Additional Names:
PARP3, IRT1, ARTD3, ADPRT3, ADPRTL2, ADPRTL3, PADPRT-3
Application Note:
PARP3 antibody can be used for detection of PARP3 by ELISA at 1:62500. PARP3 antibody can be used for detection of PARP3 by western blot at 1.0-2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. PARP3 is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
Background References:
  • Augustin, A., et al., (2003) J. Cell. Sci. 116 (Pt 8), 1551-1562.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP3.
NCBI Gene ID #:
10039
NCBI Official Name:
poly (ADP-ribose) polymerase family, member 3
NCBI Official Symbol:
PARP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa, 61 kDa, 60 kDa
Protein Accession #:
NP_005476
Protein GI Number:
158634482
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Apoptosis
Swissprot #:
Q9Y6F1
User NOte:
Optimal dilutions for each application to be determined by the researcher.