FBXO25 Antibody

ProSci
Product Code: PSI-25-823
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-25-823-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store FBXO25 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Heart at 0.2-1 ug/ml.

Antibody used in WB on Human Heart at 0.2-1 ug/ml.

Further Information

Additional Names:
FBXO25, FBX25, MGC20256, MGC51975
Application Note:
FBXO25 antibody can be used for detection of FBXO25 by ELISA at 1:312500. FBXO25 antibody can be used for detection of FBXO25 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
FBXO25 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Background References:
  • Hagens, O., (2006) Biochim. Biophys. Acta 1760 (1), 110-118.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBXO25.
NCBI Gene ID #:
26260
NCBI Official Name:
F-box protein 25
NCBI Official Symbol:
FBXO25
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
NP_036305
Protein GI Number:
34878757
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Apoptosis ,Homeostasis
Swissprot #:
Q8TCJ0
User NOte:
Optimal dilutions for each application to be determined by the researcher.