WDR4 Antibody

ProSci
Product Code: PSI-29-552
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-29-552-100ul100ul£609.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store WDR4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

1 / 2
Antibody used in WB on Human HepG2 at 1.25 ug/ml.
2 / 2

Antibody used in WB on Human HepG2 at 1.25 ug/ml.

Further Information

Additional Names:
WDR4, TRM82, TRMT82
Application Note:
WDR4 antibody can be used for detection of WDR4 by ELISA at 1:62500. WDR4 antibody can be used for detection of WDR4 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
WDR4 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.
Background References:
  • Michaud, J., (2000) Genomics 68 (1), 71-79.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WDR4.
NCBI Gene ID #:
10785
NCBI Official Name:
WD repeat domain 4
NCBI Official Symbol:
WDR4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa, 45 kDa
Protein Accession #:
NP_387510
Protein GI Number:
16445430
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Apoptosis ,Homeostasis
Swissprot #:
P57081
User NOte:
Optimal dilutions for each application to be determined by the researcher.