AKT1S1 Antibody
| Code | Size | Price |
|---|
| PSI-26-278-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store AKT1S1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
AKT1S1, Lobe, MGC2865, PRAS40
Application Note:
AKT1S1 antibody can be used for detection of AKT1S1 by ELISA at 1:62500. AKT1S1 antibody can be used for detection of AKT1S1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K)-AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).
Background References:
- Fonseca, B.D., (2008) Biochem. J. 411 (1), 141-149.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AKT1S1.
NCBI Gene ID #:
84335
NCBI Official Name:
AKT1 substrate 1 (proline-rich)
NCBI Official Symbol:
AKT1S1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
NP_115751
Protein GI Number:
400153980
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q96B36
User NOte:
Optimal dilutions for each application to be determined by the researcher.