C2orf25 Antibody

ProSci
Product Code: PSI-26-997
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-26-997-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store C2orf25 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Muscle at 0.2-1 ug/ml.

Antibody used in WB on Human Muscle at 0.2-1 ug/ml.

Further Information

Additional Names:
C2orf25, CL25022, cblD, C2orf25
Application Note:
C2orf25 antibody can be used for detection of C2orf25 by ELISA at 1:62500. C2orf25 antibody can be used for detection of C2orf25 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The function of C2orf25 remains unknown.Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to adenosylcobalamin in mitochondria and to methylcobalamin in cytoplasm is necessary for homeostasis of methylmalonic acid and homocysteine. C2ORF25 encodes a protein involved in an early step of cobalamin metabolism (Coelho et al., 2008 [PubMed 18385497]).
Background References:
  • Coelho, D., (2008) N. Engl. J. Med. 358 (14), 1454-1464.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human C2orf25.
NCBI Gene ID #:
27249
NCBI Official Name:
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
NCBI Official Symbol:
MMADHC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
NP_056517
Protein GI Number:
7661548
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q9H3L0
User NOte:
Optimal dilutions for each application to be determined by the researcher.