EME1 Antibody

ProSci
Product Code: PSI-26-729
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-26-729-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store EME1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human 293T at 0.2-1 ug/ml.

Antibody used in WB on Human 293T at 0.2-1 ug/ml.

Further Information

Additional Names:
EME1, FLJ31364, MMS4L, SLX2A
Application Note:
EME1 antibody can be used for detection of EME1 by ELISA at 1:312500. EME1 antibody can be used for detection of EME1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication.EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]).
Background References:
  • Taylor, E.R. (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (10), 3757-3762.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EME1.
NCBI Gene ID #:
146956
NCBI Official Name:
essential meiotic structure-specific endonuclease 1
NCBI Official Symbol:
EME1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
NP_689676
Protein GI Number:
260764007
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q96AY2
User NOte:
Optimal dilutions for each application to be determined by the researcher.