FBXL16 Antibody

ProSci
Product Code: PSI-31-301
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-31-301-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store FBXL16 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HeLa at 0.2-1 ug/ml.

Antibody used in WB on Human HeLa at 0.2-1 ug/ml.

Further Information

Additional Names:
FBXL16, C16orf22, FLJ33735, Fbl16, MGC33974, c380A1.1
Application Note:
FBXL16 antibody can be used for detection of FBXL16 by ELISA at 1:62500. FBXL16 antibody can be used for detection of FBXL16 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
FBXL16 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXL16, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Background References:
  • Martin, J., (2004) Nature 432 (7020), 988-994?.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBXL16.
NCBI Gene ID #:
146330
NCBI Official Name:
F-box and leucine-rich repeat protein 16
NCBI Official Symbol:
FBXL16
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
NP_699181
Protein GI Number:
289666746
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q8N461
User NOte:
Optimal dilutions for each application to be determined by the researcher.