FN3KRP Antibody
| Code | Size | Price |
|---|
| PSI-27-199-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store FN3KRP antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
FN3KRP, FLJ12171, FN3KL
Application Note:
FN3KRP antibody can be used for detection of FN3KRP by ELISA at 1:1562500. FN3KRP antibody can be used for detection of FN3KRP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]).
Background References:
- Szwergold, B., (2007) Biochem. Biophys. Res. Commun. 361 (4), 870-875.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FN3KRP.
NCBI Gene ID #:
79672
NCBI Official Name:
fructosamine 3 kinase related protein
NCBI Official Symbol:
FN3KRP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
NP_078895
Protein GI Number:
20149680
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q9HA64
User NOte:
Optimal dilutions for each application to be determined by the researcher.