GCHFR Antibody
| Code | Size | Price |
|---|
| PSI-25-878-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store GCHFR antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
GCHFR, GFRP, HsT16933, MGC138467, MGC138469, P35
Application Note:
GCHFR antibody can be used for detection of GCHFR by ELISA at 1:312500. GCHFR antibody can be used for detection of GCHFR by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
Background References:
- Ohta, E., (2006) Arch. Neurol. 63 (11), 1605-1610.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GCHFR.
NCBI Gene ID #:
2644
NCBI Official Name:
GTP cyclohydrolase I feedback regulator
NCBI Official Symbol:
GCHFR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
10 kDa
Protein Accession #:
NP_005249
Protein GI Number:
4885257
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
P30047
User NOte:
Optimal dilutions for each application to be determined by the researcher.