GEFT Antibody
| Code | Size | Price |
|---|
| PSI-26-792-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store GEFT antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
GEFT, p63RhoGEF, GEFT
Application Note:
GEFT antibody can be used for detection of GEFT by ELISA at 1:312500. GEFT antibody can be used for detection of GEFT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange.The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]).
Background References:
- Lutz, S., (2007) Science 318 (5858), 1923-1927.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GEFT.
NCBI Gene ID #:
115557
NCBI Official Name:
Rho guanine nucleotide exchange factor (GEF) 25
NCBI Official Symbol:
ARHGEF25
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
64 kDa
Protein Accession #:
NP_891992
Protein GI Number:
150417975
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q86VW2
User NOte:
Optimal dilutions for each application to be determined by the researcher.