IL18RAP Antibody
| Code | Size | Price |
|---|
| PSI-29-706-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store IL18RAP antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
IL18RAP, ACPL, CDw218b, MGC120589, MGC120590, CD218b, IL-1R7, IL18RB, IL-1R-7, IL-18RAcP, IL-1RAcPL, IL-18Rbeta, IL-18R-beta
Application Note:
IL18RAP antibody can be used for detection of IL18RAP by ELISA at 1:312500. IL18RAP antibody can be used for detection of IL18RAP by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
IL18RAP is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
Background References:
- Fukushima, K., (2005) J. Biol. Chem. 280 (18), 18056-18062.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IL18RAP.
NCBI Gene ID #:
8807
NCBI Official Name:
interleukin 18 receptor accessory protein
NCBI Official Symbol:
IL18RAP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
66 kDa
Protein Accession #:
NP_003844
Protein GI Number:
4504657
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane ,Signal Transduction ,Immunology
Swissprot #:
O95256
User NOte:
Optimal dilutions for each application to be determined by the researcher.