KPNA1 Antibody
| Code | Size | Price |
|---|
| PSI-26-909-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store KPNA1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
KPNA1, IPOA5, NPI-1, RCH2, SRP1
Application Note:
KPNA1 antibody can be used for detection of KPNA1 by ELISA at 1:62500. KPNA1 antibody can be used for detection of KPNA1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Recombination activating proteins RAG1 and RAG2 regulate and mediate V (D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. KPNA1 interacts with RAG1 and may play a role in V (D)J recombination.Recombination activating proteins RAG1 and RAG2 regulate and mediate V (D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V (D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
- Theodore, M., (2008) J. Biol. Chem. 283 (14), 8984-8994.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KPNA1.
NCBI Gene ID #:
3836
NCBI Official Name:
karyopherin alpha 1 (importin alpha 5)
NCBI Official Symbol:
KPNA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
NP_002255
Protein GI Number:
222144293
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
P52294
User NOte:
Optimal dilutions for each application to be determined by the researcher.