KPNA4 Antibody

ProSci
Product Code: PSI-26-912
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-26-912-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store KPNA4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HeLa at 0.2-1 ug/ml.
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Antibody used in WB on Human MCF7 at 1 ug/ml.
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Antibody used in WB on Human Hela at 1 ug/ml.

Antibody used in WB on Human HeLa at 0.2-1 ug/ml.
Antibody used in WB on Human MCF7 at 1 ug/ml.
Antibody used in WB on Human Hela at 1 ug/ml.

Further Information

Additional Names:
KPNA4, IPOA3, MGC12217, MGC26703, QIP1, SRP3
Application Note:
KPNA4 antibody can be used for detection of KPNA4 by ELISA at 1:1562500. KPNA4 antibody can be used for detection of KPNA4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. KPNA4 shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
  • Yeung, P.L., (2008) J. Cell. Biochem. 103 (2), 456-470.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KPNA4.
NCBI Gene ID #:
3840
NCBI Official Name:
karyopherin alpha 4 (importin alpha 3)
NCBI Official Symbol:
KPNA4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
NP_002259
Protein GI Number:
4504901
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
O00629
User NOte:
Optimal dilutions for each application to be determined by the researcher.