SPDYA Antibody

ProSci
Product Code: PSI-27-077
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-27-077-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SPDYA antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HeLa at 0.2-1 ug/ml.

Antibody used in WB on Human HeLa at 0.2-1 ug/ml.

Further Information

Additional Names:
SPDYA, MGC110856, MGC57218, SPDY1, SPY1, RINGO3, RINGOA
Application Note:
SPDYA antibody can be used for detection of SPDYA by ELISA at 1:62500. SPDYA antibody can be used for detection of SPDYA by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SPDYA regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.
Background References:
  • McAndrew, C.W., (2007) Cell Cycle 6 (15), 1937-1945.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPDYA.
NCBI Gene ID #:
245711
NCBI Official Name:
speedy/RINGO cell cycle regulator family member A
NCBI Official Symbol:
SPDYA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
NP_877433
Protein GI Number:
60498969
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q5MJ70
User NOte:
Optimal dilutions for each application to be determined by the researcher.