TINF2 Antibody
| Code | Size | Price |
|---|
| PSI-27-156-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TINF2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
TINF2, TIN2, DKCA3
Application Note:
TINF2 antibody can be used for detection of TINF2 by ELISA at 1:1562500. TINF2 antibody can be used for detection of TINF2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
TINF2 is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. It plays a role in shelterin complex assembly.
Background References:
- Kim, S.H., (2008) J. Cell Biol. 181 (3), 447-460.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TINF2.
NCBI Gene ID #:
26277
NCBI Official Name:
TERF1 (TRF1)-interacting nuclear factor 2
NCBI Official Symbol:
TINF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
NP_001092744
Protein GI Number:
151101266
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q9BSI4
User NOte:
Optimal dilutions for each application to be determined by the researcher.