TPH2 Antibody

ProSci
Product Code: PSI-28-013
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-28-013-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Canine (dog)
  • Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TPH2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.

Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.

Further Information

Additional Names:
TPH2, NTPH, ADHD7
Application Note:
TPH2 antibody can be used for detection of TPH2 by ELISA at 1:62500. TPH2 antibody can be used for detection of TPH2 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Tryptophan hydroxylase (TPH; EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.
Background References:
  • Walther, D.J., et al., (2003) Science 299 (5603), 76.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TPH2.
NCBI Gene ID #:
121278
NCBI Official Name:
tryptophan hydroxylase 2
NCBI Official Symbol:
TPH2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
NP_775489
Protein GI Number:
31795563
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q8IWU9
User NOte:
Optimal dilutions for each application to be determined by the researcher.